3-Dec-2019: A new vaccine against rotavirus launched

Vice President of India, Mr. M Venkaiah Naidu launched a new generation vaccine against rotavirus developed under a public-private partnership project involving the Department of Biotechnology in the Union Ministry of Science and Technology and Hyderabad-based Bharat Biotech and other international organisations.

Welcoming the new vaccine, Mr. Naidu urged media and medical professionals to create awareness about various health problems. There is a need for vaccination at the right time. While the government is doing its best, medical professionals should also take upon themselves the responsibility to remove apprehension about vaccination for prevention of diseases and to better the health of the nation and its people.

The Chairman and Managing Director of Bharat Biotech, Dr. Krishna Ella, said, the new vaccine is cost-effective as it is highly effective and has low cold chain footprint. It will be available in multi dose vials, resulting in savings of about US dollars 0.30 per dose in supply chain and delivery costs.

He also noted that his company has invested about US dollars 20 million to develop new manufacturing facilities and supporting infrastructure in its Genome Valley plant in Hyderabad, with an installed manufacturing capacity of about 200 million doses per year. The project was supported in part by the Bill & Melinda Gates Foundation.

The vaccine named “ROTAVAC 5D” has been evaluated in clinical trials in India and other countries. It is safe, effective and affordable, besides being cross-protective against a variety of rotavirus strains. The study results showed clear evidence of protection across different rotavirus strains and continued efficacy in the second year of life. Currently, over 25 countries have granted patents for it.

The vaccine was a miniaturized vaccine, delivering the product with a dose volume of a mere 0.5 milli litre. It enables complete delivery of the antigenic payload in 5 drops, avoiding spit-ups observed with larger dose volumes.

The vaccine can be stored at two to eight degrees Celsius for 24 months and is stable at 37 degree Celsius for 7 days. It will be available in multi-dose vials with cold chain footprints of about four cubic centimetre per dose. It has the smallest cold chain footprint for any rotavirus vaccine.

The occasion also marked the achievement of 100 million doses of worldwide supplies of the company’s ROTAVAC vaccine. The milestone was reached within two years of WHO Prequalification.