2-Aug-2022: Measures to tackle Black Marketing of Blood

It is primarily the responsibility of the State/UT Government to take concrete steps to prevent illegal activities taking place in blood banks and during blood transfusion. Government has made registration of blood banks mandatory as per the provisions of Drugs and Cosmetic Act and Rules thereunder. Further, Government has notified Drugs and Cosmetics (Second Amendment) Rules, 2020 which pertain to functioning of Blood Banks/centres, Blood processing and related matters. The implementation & monitoring of aforesaid Act and Rules is within the ambit of the States/UTs. A letter has been issued to States/UTs to take concrete steps for prevention of such illegal activities.

Further, the e-RaktKosh web portal of Government of India, provides the interface for Blood Banks data management and integration. For this, all blood banks have been advised to register on e-RaktKosh web-portal.

It is also the primary responsibility of the State/UT Government to ensure the establishment of blood banks as per their need. The policy of the Government advocates for a hub and spoke approach towards transfusion services, wherein blood is collected and processed in the hubs, which are high volume blood banks and distributed through spokes, which are smaller blood banks and blood storage centers. The requirement of blood banks depends upon the health infrastructure of the area. However, blood storage centres can be established in remote areas to meet the emergency requirement of blood, which may be attached to blood banks.

Support is provided to States/UTs to strengthen their healthcare system including strengthening existing blood banks/supporting new blood banks and blood storage units based on the proposals submitted by the States through National Health Mission. Government of India through Blood Transfusion Services also supports 1131 Blood Banks in the public and charitable sector in respect of manpower, procurement of Blood Bags and testing kits, conducting Voluntary Blood Donation (VBD) camps and Information Education Communication (IEC) activities etc. In addition, Mobile vans for Blood collection and blood transfusion vans are provided to the States/UTs.

27-Jul-2022: Measures to Address Malnutrition 

Government has accorded high priority to the issue of malnutrition and is making serious efforts to address this issue. POSHAN Abhiyaan, a flagship scheme of the Government was launched in 2018 to address the malaise of malnutrition by adopting a synergised and result oriented approach. Further, to address various policy and systemic needs, the Integrated Child Development Scheme and Anganwadi Services schemes were re-evaluated in respect of programme design, implementation process, outcome and impact and for re-assessing the relevance of the programme in achieving its aims and goals. The efforts under the Supplementary Nutrition Programme under Anganwadi Services, Scheme for Adolescent Girls and POSHAN Abhiyaan have been re-aligned as ‘Saksham Anganwadi and POSHAN 2.0’ for maximizing nutritional outcomes. It seeks to address the challenges of malnutrition in children, adolescent girls, pregnant women and lactating mothers through a strategic shift in nutrition content and delivery and by creation of a convergent eco-system to develop and promote practices that nurture health, wellness and immunity.

POSHAN Abhiyaan aims to reduce malnutrition in the country by adopting a synergised and result oriented approach. The targets laid down under the Abhiyaan are as under:

 Sl.No

Objective

Target

1.

Prevent and reduce Stunting in children (0- 6 years)

@ 2% p.a.

2.

Prevent and reduce under-nutrition (underweight prevalence) in children (0-6 years)

@ 2% p.a.

3.

Reduce the prevalence of anaemia among young Children(6-59 months)

@ 3% p.a.

4.

Reduce the prevalence of anaemia among Women and Adolescent Girls in the age group of 15-49 years.

@ 3% p.a.

5.

Reduce Low Birth Weight (LBW).

@ 2% p.a.

The estimated number of underweight, malnourished and severely malnourished children under 5 years of age is obtained under National Family Health Survey (NFHS) conducted by the Ministry of Health & Family Welfare. As per the recent report of NFHS-5 (2019-21), the nutrition indicators for children under 5 years have improved as compared with NFHS-4 (2015-16). Stunting has reduced from 38.4% to 35.5%, Wasting has reduced from 21.0% to 19.3% and Underweight prevalence has reduced from 35.8% to 32.1%. Further percentage of women (15-49 years) whose BMI is below normal has reduced from 22.9 in NFHS-4 to 18.7 in NFHS-5.

The efforts under the Supplementary Nutrition Programme under Anganwadi Services and POSHAN Abhiyaan have been rejuvenated and converged as ‘Saksham Anganwadi and POSHAN 2.0’ (Mission Poshan 2.0). It seeks to address the challenges of malnutrition in children, adolescent girls, pregnant women and lactating mothers through a strategic shift in nutrition content and delivery and by creation of a convergent eco-system to develop and promote practices that nurture health, wellness and immunity.

Poshan 2.0 shall focus on Maternal Nutrition, Infant and Young Child Feeding Norms, Treatment of MAM/SAM and Wellness through AYUSH. It will rest on the pillars of Convergence, Governance, and Capacity-building. Poshan Abhiyan will be the key pillar for Outreach and will cover innovations related to nutritional support, ICT interventions, Media Advocacy and Research, Community Outreach and Jan Andolan.

Under Poshan 2.0, focus is on diet diversity, food fortification, leveraging traditional systems of knowledge and popularizing use of millets. Nutrition awareness strategies under Poshan 2.0 aim to develop sustainable health and well-being through regional meal plans to bridge dietary gaps. Strategy of Jan Andolan, was developed to strengthen convergent actions across multiple stakeholders with focus on exclusive breast-feeding, complimentary feeding, growth monitoring, prevention of diarrhoea, hygiene, water and sanitation, anemia prevention, importance of Poshan Vatikas for cultivation of local vegetables, medicinal plants/herbs and fruits at the community level, etc. Poshan Abhiyaan has provided a strong platform for targeted home visits, community-based events (CBEs) and growth monitoring with greater emphasis placed on home visits to promote maternal, infant and young child nutrition practices. More than 40 crore activities have been carried out under Poshan Maah and Poshan Pakhwada and 3.70 lakh CBEs have been conducted since the launch of the Abhiyaan. Best practices have been disseminated through zonal work-shops to address the challenges of malnutrition.

6-Apr-2022: Malnutrition Free India

Government has accorded high priority to the issue of malnutrition and is making serious efforts to address this issue. Government implements Anganwadi Services Scheme, POSHAN Abhiyaan, Pradhan Mantri Matru Vandana Yojana and Scheme for Adolescent Girls under the Umbrella Integrated Child Development Services Scheme (ICDS) as targeted interventions for Children under 6 years, Pregnant Women and Lactating Mothers and Adolescent Girls, throughout the country. POSHAN Abhiyaan aims to reduce malnutrition in a phased manner, through a synergised and result oriented approach. Further, Mission Poshan 2.0, an integrated nutrition support programme has been announced in budget 2021-22 for all States/UTs. It seeks to strengthen nutritional content, delivery, outreach and outcomes with focus on developing practices that nurture health, wellness and immunity to disease and malnutrition. All these schemes address in one or other aspects related to nutrition and have the potential to improve nutritional outcomes in the country.

Global Hunger Index (GHI) is published by ‘Concern Worldwide & Welthungerhilfe. The GHI scores are based on the values of four component indicators, viz., Undernourishment among population, Child Wasting, Child Stunting and Child Mortality. GHI is a tool for measuring and tracking hunger at global, regional, and country levels. Global Hunger Index (GHI) does not reflect India’s true picture as it is a flawed measure of 'Hunger'. It should not be taken at face value as it is neither appropriate nor representative of hunger prevalent in a country. Out of its four indicators, only one indicator, i.e., undernourishment, is directly related to hunger. The indicator "undernourishment among population" in GHI is obtained through a gallup survey, which has completely disregarded Government’s economic response to Covid-19 of providing free food grains to 80 crore National Food Security Act beneficiaries under Pradhan Mantri Garib Kalyan Anna Yojna.

The data on nutritional indicators in the country on the other hand, is captured under the National Family Health Surveys conducted periodically by the Ministry of Health and Family Welfare. Under the Survey, the level of malnutrition among children is assessed using the WHO standards and for adults the Body Mass Index cut-offs recommended by WHO are used to assess the prevalence of under and over nutrition. Further, NFHS also provides comprehensive information on other determinants of malnutrition, viz., prevalence of micronutrient deficiencies like anaemia, food intake and infant and young child feeding and care practices including data on immunization, maternal health and nutrition, etc. The data provided by the national level survey is used to guide policies and programmes to address the nutritional challenges faced by the country.

25-Mar-2022: Initiatives To Reduce Mortalities Due To Malnutrition

There are 1080 Nutrition Rehabilitation Centres (NRCs) operational across the country. These NRCs provide medical and nutritional care of the admitted sick children with Severe Acute Malnutrition (SAM), including the tribal sick SAM children.


Government of India is taking some initiatives to reduce the mortalities due to malnutrition. Some of the key measures are as under:

  1. Nutritional Rehabilitation Centre: As per Operational Guidelines on Facility Based Management of Children with Severe Acute Malnutrition released in 2011, Nutrition Rehabilitation Centre (NRC) is a unit in a health facility where children with Severe Acute Malnutrition (SAM) are admitted and managed. The unit should be a distinct area within the health facility and should be in proximity to the pediatric ward/inpatient facility.
  2. Integrated Child Development Schemes (ICDS): Launched on 2nd October, 1975, the Integrated Child Development Services (ICDS) Scheme is one of the flagship programmes of the Government of India, implemented by Ministry of Women and Child Development. It is the foremost symbol of country’s commitment to its children and nursing mothers, as a response to the challenge of providing pre-school non-formal education on one hand and breaking the vicious cycle of malnutrition, morbidity, reduced learning capacity and mortality on the other. The beneficiaries under the Scheme are children in the age group of 0-6 years, pregnant women and lactating mothers.

The ICDS Scheme offers a package of six services, viz. (a) Supplementary Nutrition (b) Pre-school non-formal education (c) Nutrition & health education (d) Immunization (e) Health check-up and (f) Referral services. The last three services are majorly related to health and are financially and technically supported by Ministry/Department of Health and Family Welfare implemented through the State.

  1. Poshan Abhiyan is a multi-ministerial convergence mission with the vision to ensure attainment of malnutrition free India by 2022. The objective of POSHAN Abhiyaan to reduce stunting in identified Districts of India with the highest malnutrition burden by improving utilization of key Anganwadi Services and improving the quality of Anganwadi Services delivery.

The Ministry of Women and Child Development (MWCD) is implementing POSHAN Abhiyaan in phased manner. There are a number of schemes directly/indirectly affecting the nutritional status of children (0-6 year's age) and pregnant women and lactating mothers.

  1. Infant and young child feeding practices: GOI has released a guideline on Infant and young child feeding practices to improve the cognitive development, enhance weight gain and to prevent malnutrition among children. As per the guidelines for enhancing optimal infant and young child feeding practices 2013 which includes practices of initiating breast feeding within one hour of birth, exclusive breast feeding for the first 6 months of life, initiation of appropriate complementary feeding from the age of 6 months, continued breast feeding for 2 years and beyond.

Outpatient services are also provided, outpatient services of public health facilities comprising of:

  • Antenatal clinic
  • IYFC counselling centre
  • Sick child consultation in outpatient department
  1. Kangaroo Mother Care (KMC) and optimal feeding of low-birth-weight infants: Public health facilities encourage for Kangaroo Mother care and optimal feeding of low-birth-weight infants- As per Operational guidelines on Kangaroo Mother care and optimal feeding of low-birth-weight infants 2014, KMC is associated with reduced incidence of severe illness including pneumonia during infancy. In most of the studies KMC has been found to be more effective than incubator care for stable newborns in providing adequate thermal care, reducing nosocomial infections, improving exclusive breastfeeding and weight gain, and fostering greater maternal and family involvement in care.

16-Mar-2022: Malnutrition among Children

The estimated number of underweight, malnourished and severely malnourished children under 5 years of age is obtained under National Family Health Survey (NFHS) conducted by the Ministry of Health & Family Welfare. As per the recent report of NFHS-5 (2019-21), the nutrition indicators for children under 5 years have improved as compared with NFHS-4 (2015-16). Stunting has reduced from 38.4% to 35.5%, Wasting has reduced from 21.0% to 19.3% and Underweight prevalence has reduced from 35.8% to 32.1%.

Government has accorded high priority to the issue of malnutrition and is implementing several schemes like Anganwadi Services, Scheme for Adolescent Girls and Pradhan Mantri Matru Vandana Yojana (PMMVY) under the Umbrella Integrated Child Development Services (ICDS) Scheme as direct targeted interventions to address the problem of malnutrition in the country. Children with Severe Acute Malnutrition are treated at the Nutrition Rehabilitation Centres established by the Ministry of Health and Family Welfare.

Further, POSHAN Abhiyaan launched on 8th March 2018, aims to reduce malnutrition in the country by adopting a synergised and result oriented approach.

Mission Poshan 2.0, an integrated nutrition support programme has been announced in budget 2021-2022 for all States/UTs. It seeks to strengthen nutritional content, delivery, outreach and outcomes with focus on developing practices that nurture health, wellness and immunity to disease and malnutrition. Steps have been taken to improve nutritional quality and testing in accredited labs, strengthen delivery and leverage technology under Poshan Tracker to improve governance. States/UTs have been advised to promote use of AYUSH systems for prevention of malnutrition and related diseases. A programme to support development of Poshan Vatikas at Anganwadi Centres to meet dietary diversity gap leveraging traditional knowledge in nutritional practices has also been taken up. Guidelines were issued for transparency and accountability in delivery of supplementary nutrition and to track nutritional outcomes on 13.01.2021.

Top 10 and Bottom 10 Districts in Stunting

State

District

Children under 5 years who are stunted (height-for-age) (%)

Top 10 Districts

   

Odisha

Jagatsinghapur

13.2

Odisha

Puri

13.8

Arunachal Pradesh

Lower Dibang Valley

14.3

Punjab

Rupnagar

15.1

Kerala

Kollam

15.5

Manipur

Bishnupur

15.5

Haryana

Jhajjar

15.6

Karnataka

Ramanagara

15.6

Manipur

Imphal West

15.6

Arunachal Pradesh

Longding

15.8

Bottom 10 Districts

   

Jharkhand

Pashchimi Singhbhum

60.6

Meghalaya

West Khasi Hills

59

Karnataka

Yadgir

57.6

Gujarat

Dahod

55.3

Bihar

Sitamarhi

54.2

Chhattisgarh

Bijapur

53.8

Bihar

Sheikhupura

53.6

Uttar Pradesh

Bahraich

52.1

Uttar Pradesh

Budaun

51.8

Uttar Pradesh

Sambhal

51.6

Top 10 and Bottom 10 Districts in Wasting

State

District

Children under 5 years who are wasted (weight-for-height) (%)

Top 10 Districts

   

Sikkim

North District

4.5

Punjab

Ludhiana

5.9

Haryana

Bhiwani

6

NCT of Delhi

New Delhi

6.8

Tamil Nadu

Coimbatore

7

Punjab

Fatehgarh Sahib

7.1

Arunachal Pradesh

Tawang

7.1

Mizoram

Aizawl

7.3

Puducherry

Mahe

7.3

Mizoram

Mamit

7.4

Bottom 10 (Wasting)

   

Assam

Karimganj

48

Gujarat

The Dangs

40.9

Maharashtra

Dhule

38.9

Maharashtra

Chandrapur

38.5

Bihar

Arwal

36.8

Bihar

Jehanabad

36.6

Gujarat

Tapi

36.6

Telangana

Komaram Bheem Asifabad

35.7

Gujarat

Panchmahal

35.7

Bihar

Sheohar

35.4

Top 10 and Bottom 10 Districts in Underweight

State

District

Children under 5 years who are underweight (weight-for-age) (%)

Top 10 Districts

   

Sikkim

South District

7.2

Arunachal Pradesh

Lower Subansiri

8.1

Arunachal Pradesh

Siang

8.8

Arunachal Pradesh

Tawang

9

Mizoram

Aizawl

9.6

Haryana

Jhajjar

9.7

Arunachal Pradesh

Lower Dibang Valley

9.7

Manipur

Churachandpur

9.8

Manipur

Imphal West

10.2

Arunachal Pradesh

East Siang

10.3

Bottom 10 Districts

   

Jharkhand

Pashchimi Singhbhum

62.4

Maharashtra

Nandurbar

57.2

Gujarat

The Dangs

53.1

Gujarat

Dahod

53

Assam

Karimganj

52.9

Bihar

Arwal

52.9

Gujarat

Narmada

52.8

Telangana

Adilabad

52

Gujarat

Panchmahal

51.9

Gujarat

Tapi

51.8

State/UT wise prevalence of Stunting, Wasting and Underweight among children under 5 years as per NFHS 5 survey

State/UT

Children under 5 years who are stunted (height-for-age) (%)

Children under 5 years who are wasted (weight-for-height) (%)

Children under 5 years who are underweight (weight-for-age) (%)

Andaman & Nicobar Islands

22.5

16

23.7

Andhra Pradesh

31.2

16.1

29.6

Assam

35.3

21.7

32.8

Bihar

42.9

22.9

41

Dadra & Nagar Haveli and Daman & Diu

39.4

21.6

38.7

Goa

25.8

19.1

24

Gujarat

39

25.1

39.7

Himachal Pradesh

30.8

17.4

25.5

Jammu & Kashmir

26.9

19

21

Karnataka

35.4

19.5

32.9

Kerala

23.4

15.8

19.7

Lakshadweep

32

17.4

25.8

Ladakh

30.5

17.5

20.4

Maharashtra

35.2

25.6

36.1

Meghalaya

46.5

12.1

26.6

Manipur

23.4

9.9

13.3

Mizoram

28.9

9.8

12.7

Nagaland

32.7

19.1

26.9

Sikkim

22.3

13.7

13.1

Telangana

33.1

21.7

31.8

Tripura

32.3

18.2

25.6

West Bengal

33.8

20.3

32.2

Arunachal Pradesh

28

13.1

15.4

Chhattisgarh

34.6

18.9

31.3

Haryana

27.5

11.5

21.5

Jharkhand

39.6

22.4

39.4

Madhya Pradesh

35.7

19

33

Odisha

31

18.1

29.7

Punjab

24.5

10.6

16.9

Rajasthan

31.8

16.8

27.6

Tamil Nadu

25

14.6

22

Uttar Pradesh

39.7

17.3

32.1

Uttarakhand

27

13.2

21

Chandigarh

25.3

8.4

20.6

Delhi

30.9

11.2

21.8

Puducherry

20

12.4

15.3

15-Dec-2021: Malnutrition-Free India

Malnourishment in children (stunting, wasting and underweight) under 5 years has reduced as per NHFS-5 (2019-21) from 38.4% to 35.5%, 21.0% to 19.3% and 35.8% to 32.1% respectively as compared to NHFS-4 (2015-16).Malnutrition among women aged 15-49 years has also reduced from 22.9% to 18.7%.

Details of funds released and utilised under POSHAN Abhiyaan & ICDS scheme from FY 2018-19 to 2020-21 are as follows:

Amount in ₹ lakhs

Scheme

Total Central Funds released from

FY 2018-19 to FY 2020-21

Total Central Funds utilization as on

31st March 2021

POSHAN Abhiyaan

4,66,824.80

2,98,555.92

ICDS

26,10,031.55

25,36,780.66

Government has accorded high priority to the issue of malnutrition and is implementing several schemes like Anganwadi Services, Scheme for Adolescent Girls and Pradhan Mantri Matru Vandana Yojana (PMMVY) under the Umbrella Integrated Child Development Services (ICDS) Scheme as direct targeted interventions to address the problem of malnutrition in the country.

Anganwadi Services Scheme aims to improve the nutritional and health status of pregnant women & lactating mothers and reduce the incidence of mortality, morbidity and malnutrition. Under the Scheme, pregnant women and lactating mothers are provided supplementary nutrition, nutrition and health education, immunization, health check-up and referral services.

Further, POSHAN Abhiyaan launched on 8th March 2018, aims to achieve improvement in nutritional status of Adolescent Girls, Pregnant Women and Lactating Mothers in a time bound manner by adopting a synergised and result oriented approach.

Mission Poshan 2.0, an integrated nutrition support programme has been announced in budget 2021-2022 for all States/UTs. It seeks to strengthen nutritional content, delivery, outreach and outcomes with focus on developing practices that nurture health, wellness and immunity to disease and malnutrition. Steps have been taken to improve nutritional quality and testing in accredited labs, strengthen delivery and leverage technology under Poshan Tracker to improve governance. States/UTs have been advised to promote use of AYUSH systems for prevention of malnutrition and related diseases. A programme to support development of Poshan Vatikas at Anganwadi Centres to meet dietary diversity gap leveraging traditional knowledge in nutritional practices has also been taken up. Guidelines were issued for transparency and accountability in delivery of supplementary nutrition and to track nutritional outcomes on 13.01.2021.

29-Jul-2021: Efforts to reduce Malnutrition among Women and Children

As per the report released by the National Family Health Survey-4 (2015-16), conducted by Ministry of Health & Family Welfare, prevalence of undernutrition among women is 22.9% as compared to male (20.2%), which is an improvement from the levels of 35.5% and 34.2% respectively reported in National Family Health Survey-3 conducted in 2005-06.

Women are at greater risk of malnutrition due to the increased nutritional needs associated with menstruation, pregnancy, and lactation. Women are also more exposed to risk factors for malnutrition such as HIV/AIDS, food insecurity and poverty. The nutritional status of women has major implications on the well-being and nutrition of all family members. The determinants of malnutrition are often intrinsically related to gender dynamics in households and communities. Improving gender dynamics is thus a necessity to prevent malnutrition.

The data on nutritional indicators is captured under the National Family Health Surveys conducted periodically by the Ministry of Health & Family Welfare, with International Institute for Population Sciences (IIPS) being the nodal agency for conducting the surveys using a standardized methodology.

To ensure consistent and accurate recording and reporting of the critical programme data, the Ministry has initiated efforts towards quality data collection, analysis for differential planning and supervision for improved action at community level as part of strengthening and systems quality improvement via ICT based application, Poshan Tracker. The Poshan Tracker is built on latest technology for ensuring real-time monitoring and providing real-time information relating to various parameters of service delivery and malnutrition under Mission Poshan 2.0.

Government implements Anganwadi Services Scheme, POSHAN Abhiyaan, Pradhan Mantri Matru Vandana Yojana and Scheme for Adolescent Girls under the Umbrella Integrated Child Development Services Scheme (ICDS) as targeted interventions for children upto the age of 6 years, Pregnant Women and Lactating Mothers and Adolescent Girls, throughout the country. POSHAN Abhiyaan aims to reduce malnutrition in a phased manner, through a life cycle approach, by adopting a synergised and result oriented approach. Target is to bring down stunting of children under 6 years from 38.4% to 25% by the year 2022. All these schemes address in one or other aspects related to nutrition and have the potential to improve nutritional outcomes in the country.

For alleviation of malnutrition, Government has announced Mission Poshan 2.0 to strengthen nutritional content, delivery, outreach and outcomes with focus on developing practices that nurture health, wellness and immunity to disease and malnutrition.

For greater transparency, accountability and quality in nutrition support programme and service delivery, streamlined guidelines dated 13.1.2021 have been issued to States/UTs. These guidelines emphasize on ensuring the quality of supplementary nutrition, highlights roles and responsibilities of duty holders, IT enabled data management and monitoring, leveraging of traditional knowledge through AYUSH, procurement and convergence for achieving good nutritional outcomes.

21-Jul-2022: Hydrophobic ingredients, in combination with obsolete antibiotics, can counter multidrug-resistant bacteria

A new ingredient that can weakly perturb bacterial membrane, thus countering bacterial resistance to multiple classes of antibiotics, can help revive the efficacy of obsolete antibiotics.

This strategy can combat the most critical group of bacteria enabling the existing antibiotic arsenal to be used again for complicated infections. It can help counter the rising menace of anti-microbial resistance.

The World Health Organization has demarcated Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacteriaceae, all of which are resistant to carbapenems as the topmost priority critical pathogens. There are a few treatment options for these bacteria triggering use of combinations of various antibiotics to treat such complicated infections. It was thus pertinent to develop novel non-conventional therapeutic strategies to deal with these pathogens.

Scientists at JNCASR, an autonomous institute of the Department of Science and Technology, have come up with the approach of revitalising the efficacy of existing antibiotics by using them in combination with antibiotic adjuvants -- ingredients that can help counter resistance to existing antibiotics. This novel idea can help strengthen the activity of obsolete antibiotics and bring them back into use for treating complicated infections.   

Ms. Geetika Dhanda and Prof. Jayanta Haldar incorporated cyclic hydrophobic moieties (portion of a molecule) in a triamine-containing compound the adjuvants thus developed weakly perturbed the membrane of bacteria. This resulted in countering of membrane-associated resistance elements like permeability barrier and expulsion of antibiotics by efflux pumps. When these adjuvants are used in combination with antibiotics that had been rendered ineffective due to such membrane-associated resistance elements, the antibiotics are potentiated, and the combination was effective in killing bacteria.

The combination of the adjuvant with antibiotics like fusidic acid, minocycline, and rifampicin inactivates multidrug-resistant Gram-negative bacteria. These include Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacteriaceae. The study published in the journal ACS Infect. Diseases, highlight the chemical intuition and extent of membrane-perturbation required for the design of non-active and non-toxic adjuvants. The choice of non-active adjuvant would also put less pressure on the bacteria to develop resistance to it. Moreover, weak membrane perturbation would result in less toxicity. 

This work requires proper validation in in-vivo model systems, followed by preclinical studies, which will further add value to the work.

15-Mar-2018: Antibiotic resistance in Egyptian vultures

A study has found that, Escherichia coli, a pathogen seen in over 90% of Egyptian vultures that migrate to northwest India to spend the winter, tend to show significant difference in resistance to antibiotics within a single season. This is due to the environment that the vultures were exposed to — carcasses, garbage, and domestic animals.

The vultures that use human-dominated landscapes as part of their life cycle were likely to act as “reservoirs and melting pots of bacterial resistance.

Escherichia coli (E. coli) is a bacteria that is surprisingly an important aspect of human intestinal tract health. Most E.coli are harmless bacteria and assist in everyday health. However the E.coli that generally make the headlines are pathogenic, which cause illnesses such as diarrhoea, or even things outside the intestinal functions.

Usually, the E. coli that causes diarrhoea is transferred through food, water, or contact with animals/people who already have E.coli. The infection usually occurs if you swallow miniscule amounts of human or animal feces (this amount is often invisible to the naked eye).

These tiny traces of feces usually comes from contaminated food such as, raw produce, raw milk, soft cheese, unpasteurized apple cider, or even dealing with a dirty diaper or an employee not thoroughly washing their hands when preparing food.